The United Nations Children's Fund (UNICEF) is an agency of the United Nations responsible for providing humanitarian and developmental aid to children worldwide.

UNICEF's emergency programme in DR Congo was the original home of ActivityInfo in 2009 and since then many country offices have adopted ActivityInfo to collect partner data related to the implementation of various projects in sectors, clusters and RRMs as well as for Monitoring & Evaluation, impact surveys and facility mapping. ActivityInfo improves data quality and facilitates decision-making in multiple cases including but not limited to the Ebola Response in DRC to the Lebanon Crisis Response Plan, the country-wide Rapid Response Mechanism in CAR and the Ukraine's refugee crisis in Romania.

“ActivityInfo changed the reporting mechanism at the beginning of the refugee crisis in the Middle East from aggregating reporting to a unique reporting system. With ActivityInfo you can with just a click, in a second, have a report about activities taking place in an area with a list of partners that are delivering the service in this specific area. From a month of inaccurate results to a couple of minutes of accurate results on one single dashboard.” — Rodolphe Ghossoub, UNICEF Lebanon